Yes, it is. Even a program as simple as Coda being able to connect to a remote server and every time you save on your computer, it will sync with your site, of course provided that the correct server settings are in place. You'll also be able to add/remove and modify CSS, HTML, PHP, etc... straight from the program as well.
It's similar to Dreamweaver's built in "Add Site" feature.
As long as you know your site's FTP information, you shouldn't run into any problems.
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