Wacom Pen or Laser Mouse? Which do you prefer? Why?

Regardless of any graphic tablet brand you prefer, or any particular mouse. What is your choice for pointing device?

For me, I've replaced almost all my "pointing" with a graphic tablet. I've always drawn a lot, so its more confortable for me. And with my Wacom and Photoshop I can certainly do things I couldn't with a mouse.

Maybe some of you guys will laugh, but I do play RTS with the tablet. A friend of mine played FPS with a trackball and he managed to make lots of headshots.

Although I doubt any pointing device can get better than mouse for FPS purposes (I love Razer mice).

If you had to choose one for your overall use, which would it be?