Yes. IE renders the margin differently from compliant browsers such as Firefox. I have run into this annoying problem on more than one occaision.

I normally use nested div's to get around this problem. I'll set the outside div to line up the text where I want it, then use another div on the inside with padding instead of margin used to set the space. Of course your solution could be different depending on what you're using it for exactly.

Do you have an example of what you're doing?